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Study identifier: NCT04889716 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CAR-T Followed by Bispecific Antibodies

Condition: Large B-cell Lymphoma · DLBCL - Diffuse Large B Cell Lymphoma  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhasePhase 2
Planned participants23
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The research study is being conducted to test the safety and effectiveness of the experimental drug mosunetuzumab (Cohort 1) or obinutuzumab and glofitamab (Cohort 2) when given after CAR (genetically modified) T cells. The study is for patients who have already received a CAR T-cell infusion. Some patients who join the study will receive mosunetuzumab, other patients later in the study may receive a different experimental drug (glofitamab, in combination with obinutuzumab).

This description comes directly from the study's public registry record.

Talk to the study team

Rachel Lundberg, PA-C  ·  215-615-5858  ·  Rachel.Lundberg@pennmedicine.upenn.edu

Kaitlin Kennard, RN  ·  215-615-5858  ·  Kaitlin.Kennard@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04889716