Condition: Inflammation · Normal Controls · Metabolic Disease · Sponsor: National Institute of Environmental Health Sciences (NIEHS)
Background: Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures. They want to collect biological and environmental samples and other data. They may use the samples to measure a range of factors, like hormones, toxins, and chemicals. This will help them improve their studies. Objective: To identify and understand how environmental exposures contribute to human disease. Eligibility: Healthy adults ages 18 and older Design: Participants will be screened with questions about their health history, demographics, and medicines they take. Participants may give blood, hair, stool, saliva, and/or urine samples. They may have a skin punch biopsy to collect skin cells. They may give fingernail or toenail clippings. They may give a sample of exhaled breath. Participants may give a sputum sample. They will inhale a saline mist and cough mucus into a cup. Participants may have their nasal passages brushed, scraped, or washed. Participants may give cheek cell samples. They will swish mouthwash and spit it into a cup. Participants who produce sperm may give samples. Participants may have bronchoscopy to collect fluid. A saline solution will be put into their lung and then suctioned out, washing areas of the lung. Participants may have a pelvic or transvaginal ultrasound. They may have lung function tests. Participants may collec…
This description comes directly from the study's public registry record.
NIEHS Join A Study Recruitment Group · (855) 696-4347 · myniehs@nih.gov
Lawrence S Kirschner, M.D. · (984) 287-3562 · lawrence.kirschner@nih.gov
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| NIEHS Clinical Research Unit (CRU) | Research Triangle Park, North Carolina, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04888923