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Study identifier: NCT04888741 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Methods of T Cell Depletion Trial (MoTD)

Condition: Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Chronic Myelomonocytic Leukemia  ·  Sponsor: University of Birmingham

PhasePhase 2
Planned participants400
Who can joinAll sexes, 16 Years to 70 Years
Healthy volunteersNo

About this study

A multi-centre phase II trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin vs. Calcineurin inhibitor or Sirolimus-based post-transplant cyclophosphamide.

This description comes directly from the study's public registry record.

Talk to the study team

MoTD Trial  ·  0121 371 7859  ·  MoTD@trials.bham.ac.uk

Andrea Dr Hodgkinson  ·  0121 371 4365  ·  A.Hodgkinson@bham.ac.uk

Always discuss trial participation with your own doctor first.

Locations (17)

University Hospital of WalesCardiff, Wales, United KingdomRecruiting
Queen Elizabeth HospitalBirmingham, United KingdomRecruiting
Bristol Haematology and Oncology CentreBristol, United KingdomRecruiting
Addenbrookes HospitalCambridge, United KingdomRecruiting
Queen Elizabeth Hospital GlasgowGlasgow, United KingdomRecruiting
St Jame's University HospitalLeeds, United KingdomRecruiting
University College London HospitalLondon, United KingdomRecruiting
King's College HospitalLondon, United KingdomRecruiting
Hammersmith HospitalLondon, United KingdomRecruiting
Manchester Royal InfirmaryManchester, United KingdomRecruiting
The ChristieManchester, United KingdomRecruiting
Freeman HospitalNewcastle upon Tyne, United KingdomRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04888741