Condition: Blood Pressure · Sponsor: The University of Texas Health Science Center, Houston
An international randomized trial to test the primary hypothesis that perioperative tight blood pressure management reduces a composite of major perfusion-related complications (myocardial injury, stroke, non-fatal cardiac arrest, Stage 2-3 acute kidney injury, deep or organ-space infection, sepsis, and death) in the 30 days after major non-cardiac surgery. The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg (tight pressure management); or, 2) routine intraoperative blood pressure management (routine pressure management).
This description comes directly from the study's public registry record.
Valerie L. Anderson, BS · (713) 500-4383 · Valerie.L.Anderson@uth.tmc.edu
Daniel Sessler, MD · (713) 500-3062 · Daniel.Sessler@uth.tmc.edu
Always discuss trial participation with your own doctor first.
| University of Nebraska Medical Center | Omaha, Nebraska, United States | Completed |
| Wake Forest University | Wake Forest, North Carolina, United States | Completed |
| MetroHealth Medical Center | Cleveland, Ohio, United States | Recruiting |
| Cleveland Clinic Fairview Hospital | Cleveland, Ohio, United States | Completed |
| Cleveland Clinic Main Campus | Cleveland, Ohio, United States | Completed |
| The University of Texas Health Science Center at Houston | Houston, Texas, United States | Recruiting |
| Beijing Shijitan Hospital, Capital Medical University | Beijing, China | Recruiting |
| Peking Union Medical College Hospital | Beijing, China | Recruiting |
| Peking University First Hospital | Beijing, China | Recruiting |
| West China University Hospital | Chengdu, China | Recruiting |
| Prince of Wales Hospital, Chinese University of Hong Kong, Shatin | Hong Kong, China | Recruiting |
| Renji Hospital, Shanghai Jiaotong University School of Medicine | Shanghai, China | Recruiting |
+ 8 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04884802