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Study identifier: NCT04881487 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Additional Treatment for Isolated Local Pancreatic Cancer Recurrence Using Stereotactic Body Radiation Therapy

Condition: Recurrent Pancreatic Ductal Adenocarcinoma  ·  Sponsor: UMC Utrecht

PhaseNA
Planned participants174
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A randomized controlled trial, nested within an existing prospective cohort (Dutch Pancreatic Cancer Project; PACAP) according to the 'trials within cohorts' (TwiCs) design in which the effect of additional local ablative therapy compared to current standard of care alone, on survival after recurrence in patients with isolated local pancreatic ductal adenocarcinoma (PDAC) recurrence. The most important secondary endpoint is quality of life. Other secondary endpoints are treatment response, acute and late toxicity, overall survival, progression-free survival, local progression-free survival, distant metastases free survival and reasons for non-eligibility or exclusion.

This description comes directly from the study's public registry record.

Talk to the study team

M. P.W. Intven, MD PhD  ·  0630866525  ·  m.intven@umcutrecht.nl

Always discuss trial participation with your own doctor first.

Locations (3)

Amsterdam University Medical Center, VUmcAmsterdam, North Holland, NetherlandsRecruiting
Erasmus University Medical CenterRotterdam, South Holland, NetherlandsRecruiting
University Medical Center UtrechtUtrecht, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT04881487