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Study identifier: NCT04879121 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

Condition: Locally Advanced Malignant Solid Neoplasm · Metastatic Malignant Solid Neoplasm  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants13
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies the effect of larotrectinib in treating patients with NTRK gene amplification positive solid tumors that have spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic). Larotrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04879121