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Study identifier: NCT04875702 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Condition: Gout  ·  Sponsor: Massachusetts General Hospital

PhasePhase 4
Planned participants650
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.

This description comes directly from the study's public registry record.

Talk to the study team

Ana D Fernandes, MA  ·  617-643-2140  ·  adfernandes@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (7)

The University of Alabama at BirminghamSouth Birmingham, Alabama, United StatesNot Yet Recruiting
UCLA HealthSanta Monica, California, United StatesNot Yet Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Brigham and Women's Hospital (BWH)Boston, Massachusetts, United StatesRecruiting
Boston Medical Center (BMC)Boston, Massachusetts, United StatesNot Yet Recruiting
NYU LangoneNew York, New York, United StatesRecruiting
West Virginia University (Including Mobile Clinical Trials Unit)Morgantown, West Virginia, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04875702