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Study identifier: NCT04875052 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

Condition: Osteoarthritis, Knee · Anterior Cruciate Ligament Injuries · Post-traumatic Osteoarthritis  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants114
Who can joinAll sexes, 16 Years to 35 Years
Healthy volunteersNo

About this study

The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who have undergone anterior cruciate ligament reconstruction surgery (ACLR). The main objectives are to compare the effects of Standard rehabilitation vs. rehabilitation that includes whole body vibration (WBV) or local muscle vibration (LMV) on: * Quadriceps muscle function * Gait biomechanics linked to post-traumatic knee osteoarthritis development * Patient self-report outcomes * MRI indicators of knee joint health and muscle quality * Landing biomechanics linked to secondary ACL injury risk * Evidence-based return-to-physical-activity criteria Participants will be assigned to 1 of 3 groups (standard rehabilitation, standard rehabilitation + WBV, or standard rehabilitation + LMV) and will complete assessments of quadriceps function, gait biomechanics, landing biomechanics, functional ability, patient-report outcomes, and MRI 1, 6, and 12 months after ACLR. Researchers will compare the groups to see if vibration embedded in ACLR rehabilitation improves joint health outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Troy Blackburn, PhD  ·  919-843-2021  ·  troyb@email.unc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

MOTION Science InstituteChapel Hill, North Carolina, United StatesRecruiting
Womack Army Medical CenterChapel Hill, North Carolina, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04875052