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Study identifier: NCT04874038 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Condition: Post-mastectomy Pain Syndrome · Breast Cancer · Pain, Postoperative  ·  Sponsor: University Health Network, Toronto

PhasePhase 3
Planned participants1602
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months after breast cancer surgery.

This description comes directly from the study's public registry record.

Talk to the study team

James Khan  ·  416-340-4800  ·  James.Khan@medportal.ca

Nour Ayach  ·  416-340-4800  ·  Nour.Ayach@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (17)

Foothills Medical CentreCalgary, Alberta, CanadaRecruiting
Sturgeon Community HospitalEdmonton, Alberta, CanadaRecruiting
Eastern Health- Health Sciences CentreSt. John's, Newfoundland and Labrador, CanadaRecruiting
IWKHalifax, Nova Scotia, CanadaRecruiting
Juravinski HospitalHamilton, Ontario, CanadaRecruiting
North York General HospitalNorth York, Ontario, CanadaRecruiting
The Ottawa HospitalOttawa, Ontario, CanadaRecruiting
Thunder Bay Regional Health Sciences CentreThunder Bay, Ontario, CanadaRecruiting
Humber River HospitalToronto, Ontario, CanadaRecruiting
Mount Sinai HospitalToronto, Ontario, CanadaRecruiting
St. Michael's HospitalToronto, Ontario, CanadaRecruiting
Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04874038