Condition: Diabetes Mellitus, Type 2 · Sponsor: Hospital de Clinicas de Porto Alegre
Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do not reach the glycemic targets, requiring adjuvant therapies. Taurine is a semi-essential amino acid with antioxidant and osmoregulatory properties, commonly used as a nutritional supplement. Pre-clinical studies show its effectiveness in reducing blood glucose and cholesterol, but there are no well-conducted clinical studies evaluating the effect of taurine on glycated hemoglobin. Additionally, animal models showed that taurine had a protective effect from diabetic nephropathy. The hypothesize of this study is that taurine administration improves the glycemic, lipid, inflammatory, and anthropometric parameters in DM2 individuals.
This description comes directly from the study's public registry record.
Beatriz D Schaan, PhD · 55 51 3359-8000 · bschaan@hcpa.edu.br
Rosane Gomez, PhD · 55 51 33082823 · rogomez@hcpa.edu.br
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| Hospital de Clínicas | Porto Alegre, Rio Grande do Sul, Brazil | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04874012