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Study identifier: NCT04873011 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Quinine Hydrochloride in Overweight Population on Food Intake, Hunger and Gut Peptide Release

Condition: Obesity  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhasePhase 1
Planned participants40
Who can joinFemale, 18 Years to 65 Years
Healthy volunteersYes

About this study

The worldwide increase in the prevalence of obesity is a cause of great concern. Pharmacological treatment options are being explored at the moment with a major focus on the hormones produced by the gastrointestinal tract which regulate hunger and satiation/satiety. Modulating the release of these hormones via bitter substances reduced appetite-related sensations and gastrointestinal motility in lean female volunteers. Intragastric administration of a quinine-solution has shown to decrease hunger sensations in healthy female volunteers. Now, we want to examine whether this effect is still seen in an overweight female population.

This description comes directly from the study's public registry record.

Talk to the study team

Wout Verbeure  ·  16373765  ·  wout.verbeure@kuleuven.be

Always discuss trial participation with your own doctor first.

Locations (1)

TARGIDLeuven, Vlaams-Brabant, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT04873011