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Study identifier: NCT04872478 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Condition: Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Mixed Phenotype Acute Leukemia  ·  Sponsor: Meryx, Inc.

PhasePhase 1
Planned participants50
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase I, open-label, non-randomized, dose escalation study in adolescents and adults with relapsed/refractory acute myeloid leukemia, acute lymphoblastic leukemia, or mixed phenotype acute leukemia. Patients will receive continuous oral MRX-2843 in 28 day cycles at predefined dose cohorts.

This description comes directly from the study's public registry record.

Talk to the study team

Meryx  ·  919-270-4667  ·  safety@meryxpharma.com

Always discuss trial participation with your own doctor first.

Locations (3)

Emory University - WINSHIP Cancer CenterAtlanta, Georgia, United StatesRecruiting
Emory University, Children's Healthcare of AtlantaAtlanta, Georgia, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04872478