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Study identifier: NCT04871191 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis

Condition: Granulomatosis With Polyangiitis · Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants42
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify the most promising therapeutic strategy for patients with granulomatosis with polyangiitis and inadequate response to standard of care therapy. It will evaluate the efficacy to induce remission of three different salvage strategies including: a combination of rituximab with addition of a conventional disease-modifying antirheumatic drugs (either methotrexate, azathioprine or mycophenolate mofetil, but preferentially methotrexate); tocilizumab; or tofacitinib.

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan London, MD  ·  +33 1 44 64 16 02  ·  jlondon@hopital-dcss.org

Alice CAMARA  ·  01 58 41 12 11  ·  alice.camara@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital de la Croix Saint SimonParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04871191