Condition: Chronic Rhinosinusitis With Nasal Polyps · Olfactory Disorder · Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
The study aims to investigate the olfactory TDI score (Threshold, Discrimination, Identification) using the Sniffin' sticks test for patients with chronic rhinosinusitis with nasal polyps (CRSwNP) on dupilumab. Twenty-seven adult patients will be followed up during the treatment with dupilumab on three visits to the Otolaryngology Clinic (Baseline, 3 months and 6 months). The primary endpoint will be the TDI score. Nasal polyp score, Quality of Olfactory Disorders - negative symptoms (QOD-NS symptom scores), SNOT-22 will be secondary endpoints.
This description comes directly from the study's public registry record.
Cristian Dihel, MD · +15196466100 · cristian.dihel@sjhc.london.on.ca
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| St. Joseph's Health Care | London, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04869436