Condition: NSCLC Stage II · NSCLC, Stage IIIA · NSCLC Stage IIIB · Sponsor: University Hospital Heidelberg
Exploratory study evaluating the potential of immune signature profiling for predicting response in patients with resectable Stage II, IIIA and select IIIB (T3N2 only) non-squamous Non-Small Cell Lung Cancer (NSCLC) to neoadjuvant ATEZOLIZUMAB plus Carboplatin/nab Paclitaxel Atezolizumab is given as intravenous infusion at a fixed dose of 1200 mg, day 1 of each 21-day cycle (every 3 weeks) for 3 cycles during the neoadjuvant treatment phase, Carboplatin at an initial dose of AUC (area under curve) 5 mg/mL/min, intravenously day 1 of each 21-day cycle for 3 cycles during the neoadjuvant treatment Phase, and Nab-Paclitaxel (Abraxane) at 100 mg/m2, intravenously day 1, 8 and 15 of each 21-day cycle for 3 cycles during the neoadjuvant treatment phase. Surgery after the 3rd cycle Atezolizumab / Carboplatin / Nab-Paclitaxel is standard procedure.
This description comes directly from the study's public registry record.
Dirk Jäger, Prof. med. · +49 6221 56 7229 · Dirk.Jaeger@med.uni-heidelberg.de
Martin Eichhorn, PD Dr. med. · +496221 396 1101 · Martin.Eichhorn@med.uni-heidelberg.de
Always discuss trial participation with your own doctor first.
| Thoraxklinik Heidelberg gGmbH | Heidelberg, BaWü, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04865250