Condition: Alcoholic Liver Disease · COVID 19 Pneumonia · Sponsor: The Cleveland Clinic
Patients with COVID-19 and comorbidities including alcohol associated liver disease (ALD) are at risk for severe illness and abrupt or sudden clinical deterioration with ventilatory failure. â-hydroxy â-methyl butyrate (HMB), a non-nitrogenous leucine metabolite with anabolic properties, increases muscle mass and contractile function and enhances immune function. We aim to study the natural course of COVID-19 in patients with ALD and test whether HMB can affect ventilatory deterioration and improve short and long-term morbidity, mortality, and recovery from critical illness in symptomatic COVID-19 patients with ALD.
This description comes directly from the study's public registry record.
Annette Bellar, MSLA · 216-445-0688 · bellara@ccf.org
Alina Tuladhar, MPH · 216-445-6268 · tuladha@ccf.org
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| Cleveland Clinic Foundation | Cleveland, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04858412