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Study identifier: NCT04857502 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer

Condition: Prostate Carcinoma · Recurrent Prostate Carcinoma  ·  Sponsor: Jonsson Comprehensive Cancer Center

PhaseEARLY_Phase 1
Planned participants30
Who can joinMale, N/A to no upper limit
Healthy volunteersNo

About this study

This exploratory study conducted under the RDRC program studies the biodistribution of 99mTc-PSMA-I\&S in patients with prostate cancer who undergo pelvic lymph node dissection. Prostate specific membrane antigen (PSMA)-targeted radio-guided surgery uses the preoperative intravenous administration of a PSMA-ligand called PSMA-imaging and surgery (I\&S) labeled with the gamma-emitter radioisotope Technetium-99m (99mTc). Giving 99mTc-PSMA-I\&S may detect PSMA-expressing lymph nodes during surgery using a gamma probe and may help guide doctors to detect prostate cancer that has spread to the lymph nodes.

This description comes directly from the study's public registry record.

Talk to the study team

Deepu Varughese  ·  310-206-7372  ·  DVarughese@mednet.ucla.edu

Ankush Sachdeva  ·  310-794-3421  ·  ASachdeva@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04857502