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Study identifier: NCT04853251 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Condition: Neovascular Age-related Macular Degeneration  ·  Sponsor: Genentech, Inc.

PhasePhase 4
Planned participants188
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: ML43000 https://forpatients.roche.com/  ·  888-662-6728 (U.S.)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. No email attachments. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (52)

Barnet Dulaney Perkins Eye CenterMesa, Arizona, United StatesRecruiting
California Retina ConsultantsBakersfield, California, United StatesCompleted
Retina Associates of Southern CaliforniaHuntington Beach, California, United StatesRecruiting
California Eye Specialists Medical group Inc.Pasadena, California, United StatesCompleted
Retinal Consultants Med GroupSacramento, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Orange County Retina Med GroupSanta Ana, California, United StatesRecruiting
Macula Retina Vitreous Research InstituteTorrance, California, United StatesRecruiting
Southwest Retina ConsultantsDurango, Colorado, United StatesCompleted
Advanced Vision Research InstituteLongmont, Colorado, United StatesRecruiting
Retina Group of New EnglandWaterford, Connecticut, United StatesWithdrawn
Retina Specialty InstitutePensacola, Florida, United StatesRecruiting

+ 40 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04853251