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Study identifier: NCT04848064 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma

Condition: Recurrent Adult T-Cell Leukemia/Lymphoma · Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma · Refractory Adult T-Cell Leukemia/Lymphoma  ·  Sponsor: John Reneau

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial is to find out the best dose, possible benefits and/or side effects of third-party natural killer cells in combination with mogamulizumab in treating patients with cutaneous T-cell lymphoma or adult T-cell leukemia/lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Immunotherapy with third-party natural killer cells, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Mogamulizumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Giving third-party natural killer cells in combination with mogamulizumab may kill more cancer cells.

This description comes directly from the study's public registry record.

Talk to the study team

The Ohio State University Comprehensive Cancer Center  ·  800-293-5066  ·  OSUCCCClinicaltrials@osumc.edu

Thomas Needham  ·  thomas.needham@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04848064