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Study identifier: NCT04846777 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Brief Smartphone Treatment Study

Condition: Generalized Anxiety Disorder  ·  Sponsor: Penn State University

PhaseNA
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Little is known about whether and how brief mindfulness therapies yield clinically beneficial effects. This gap exists despite the rapid growth of smartphone mindfulness applications and presence of mental health treatment gap. Specifically, no prior brief, smartphone mindfulness ecological momentary intervention (MEMI) has targeted generalized anxiety disorder (GAD). Moreover, although theories propose that mindfulness intervention can boost attentional control (AC), executive functioning (EF), perspective-taking, and social cognition skills they have largely gone untested. Thus, this randomized controlled trial (RCT) aims to address these gaps by assessing the efficacy of a 14-day smartphone mindfulness EMI (vs. placebo). Participants with GAD will be randomly assigned to either MEMI or self-monitoring placebo (SMP). Those in treatment will exercise multiple core mindfulness strategies (open monitoring, acceptance, attending to small moments, slowed rhythmic diaphragmatic breathing). Also, those in MEMI will be reminded before bedtime that mindfulness is a lifelong practice. Comparatively, participants assigned to SMP will only be prompted to practice self-monitoring. They will notice their thoughts, rate any distress associated with them, and will not be taught any mindfulness strategies. All prompts will occur 5 times a day, for 14 consecutive days. They will complete self-reports and neuropsychological assessments at pre-, post-, and 1-month follow-up. Multilevel modelin…

This description comes directly from the study's public registry record.

Talk to the study team

Nur Hani Zainal, M.S.  ·  917-767-7088  ·  nvz5057@psu.edu

Michelle G. Newman, Ph.D.  ·  814-883-4572  ·  mgn1@psu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Pennsylvania State UniversityUniversity Park, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04846777