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Study identifier: NCT04846140 Synced from ClinicalTrials.gov · July 28, 2026
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Optimal Non-invasive Brain Stimulation for Peripheral Vision

Condition: Glaucoma  ·  Sponsor: The Hong Kong Polytechnic University

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Glaucoma is a complex disease that can result in progressive vision loss. There are no treatments that restore vision lost to glaucoma. However, recent studies have shown that vision can be improved by non-invasive brain (NIBS) stimulation and visual training. In this study, we aim to compare and find out the optimal non-invasive brain stimulation model (transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and transcranial random noise stimulation (tRNS)) for improving peripheral vision in glaucoma patients. The proposed treatment is the application of transcranial electrical stimulation (tES) onto the participant's head, with brain stimulation aimed at the Primary Visual Cortex toward the occipital pole. The investigators hypothesize that the tES will enable higher performance in the reading task and secondary measures due to an increase in the cortical excitability of the stimulated brain cells, and tRNS will generate the greatest acute improvement in peripheral vision than either a-tDCS, tACS, or sham stimulation.

This description comes directly from the study's public registry record.

Talk to the study team

Allen Cheong, PhD  ·  852-27666108  ·  allen.my.cheong@polyu.edu.hk

Ben Thompson, PhD  ·  852-27666108  ·  ben.thompson@uwaterloo.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Allen MY CheongHong Kong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04846140