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Study identifier: NCT04845178 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults

Condition: Migraine  ·  Sponsor: AEON Biopharma, Inc.

PhasePhase 2
Planned participants797
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 2 trial will evaluate the efficacy and safety of ABP-450 for migraine prevention in adults who suffer from six or more migraine days per month. The study will enroll 765 patients across approximately 64 sites in the United States, Canada and Australia. Study subjects will be divided evenly across a low dose group, a high dose group and a placebo group. All patients will receive two treatment cycles of ABP-450 or placebo utilizing the Company's novel injection paradigm.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (62)

MDFirst ResearchChandler, Arizona, United States
Elite Clinical Studies, LLCPhoenix, Arizona, United States
Arizona Neuroscience ResearchPhoenix, Arizona, United States
Clinical Research Consortium ArizonaTempe, Arizona, United States
Axiom Research LLCColton, California, United States
Velocity Research San DiegoLa Mesa, California, United States
Collaborative Neuroscience ResearchLong Beach, California, United States
Los Angeles Headache CenterLos Angeles, California, United States
Anderson Clinical ResearchRedlands, California, United States
Artemis Institute For Clinical Research LLC - San Diego - ClinEdge - PPDSSan Diego, California, United States
Delta Waves LLC - Hunt - PPDSColorado Springs, Colorado, United States
Paradigm Clinical Research CentersWheat Ridge, Colorado, United States

+ 50 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04845178