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Study identifier: NCT04844866 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Condition: Diffuse Large B-cell Lymphoma  ·  Sponsor: Miltenyi Biomedicine GmbH

PhasePhase 2
Planned participants213
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

In the current protocol version, there are two parts. Part I is a pivotal Phase II randomised, multi-centre, open-label study to evaluate the efficacy and safety of MB-CART2019.1 compared to standard of care therapy in participants with relapsed/refractory diffuse large B-cell lymphoma, who are not eligible for high-dose chemotherapy and autologous stem cell transplantation. Part II is a Phase II single-arm, open-label, multi-centre study evaluating the efficacy and safety of MB-CART2019.1 in younger, fit participants with R-R DLBCL. Part II will start after completion of enrolment in Part I.

This description comes directly from the study's public registry record.

Talk to the study team

Mark Hess, Dr.  ·  +49 160 9897 0124  ·  mark.hess@miltenyi.com

Gregor Zadoyan, Dr.  ·  +49 2204 8306  ·  gregor.zadoyan@miltenyi.com

Always discuss trial participation with your own doctor first.

Locations (51)

LKH - Medizinische Universitaet GrazGraz, AustriaActive Not Recruiting
Universitatsklinikum Innsbruck Universitatsklinik fur Innere Medizin VInnsbruck, AustriaRecruiting
Ordensklinikum Linz GmbH ElisabethinenLinz, AustriaRecruiting
Medizinische Universitaet Wien - Allgemeines Krankenhaus der Stadt Wien (AKH)Vienna, AustriaRecruiting
Jules Bordet lnstituteAnderlecht, BelgiumRecruiting
Universitaire Ziekenhuizen Leuven - Campus GasthuisbergLeuven, BelgiumRecruiting
University Hospital Center ZagrebZagreb, CroatiaRecruiting
University Hospital Hradec KraloveHradec Králové, CzechiaRecruiting
FNsP OstravaOstrava, CzechiaRecruiting
Helsinki University Comprehensive Cancer CenterHelsinki, FinlandNot Yet Recruiting
Oulu University Central HospitalOulu, FinlandRecruiting
Turku University HospitalTurku, FinlandRecruiting

+ 39 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04844866