Condition: Liver Cancer · Lung Cancer · Breast Cancer · Sponsor: Second Affiliated Hospital of Guangzhou Medical University
Tumor infiltration lymphocytes (TILs) have been harvested from advanced cancer patients and constructed to knockout PD1 gene and express scFvs against both PD1 and CTALA4 and CARs against various antigens, followed by transfusion into the patients. The safety, tolerance, and preliminary clinical efficacy of the TILs will be evaluated.
This description comes directly from the study's public registry record.
Zhenfeng Zhang, MD, PhD · +862039195966 · zhangzhf@gzhmu.edu.cn
Bingjia He, MD · +862039195965 · 464677938@qq.com
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| Second Affiliated Hospital of Guangzhou Medical University | Guangzhou, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04842812