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Study identifier: NCT04841148 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

Condition: Breast Cancer  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhasePhase 2
Planned participants96
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast cancer patients who are found to harbor disseminated tumor cells (DTCs) in the bone marrow after definitive surgery and standard adjuvant therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Lauren Bayne, PhD  ·  215-615-2367  ·  breastcancerclinicaltrials@pennmedicine.upenn.edu

Pauleen Sanchez, BA  ·  215-615-2367  ·  breastcancerclinicaltrials@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (7)

Georgetown UniversityWashington D.C., District of Columbia, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
Indiana UniversityIndianapolis, Indiana, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Vanderbilt UniversityNashville, Tennessee, United StatesRecruiting
University of WashingtonSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04841148