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Study identifier: NCT04833894 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis

Condition: Generalized Myasthenia Gravis  ·  Sponsor: argenx

PhasePhase 2/Phase 3
Planned participants12
Who can joinAll sexes, 2 Years to 18 Years
Healthy volunteersNo

About this study

The purpose of this trial is to investigate the PK, PD, safety, and activity of efgartigimod IV in children and adolescents aged from 2 to less than 18 years of age with gMG. Trial details include: * The maximum trial duration for each individual participant will be approximately 28 weeks * The treatment duration will be 8 weeks for the dose-confirmatory part (Part A) and 18 weeks for the treatment response-confirmatory part (Part B)

This description comes directly from the study's public registry record.

Talk to the study team

Sabine Coppieters, MD  ·  857-350-4834  ·  ClinicalTrials@argenx.com

Always discuss trial participation with your own doctor first.

Locations (25)

Ann and Robert H Lurie Children's Hospital of Chicago - Main HospitalChicago, Illinois, United StatesRecruiting
University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting
University of Virginia (UVA) Health - Developmental Pediatrics ClinicCharlottesville, Virginia, United StatesRecruiting
Medizinische Universitat WienVienna, AustriaCompleted
Universitair Ziekenhuis AntwerpenAntwerp, BelgiumRecruiting
Alberta Childrens HospitalCalgary, CanadaRecruiting
British Columbia Children's HospitalVancouver, CanadaRecruiting
AP-HM - Hopital de la TimoneMarseille, FranceRecruiting
Assistance Publique Hopitaux de Paris (AP-HP) - Hopital Necker-Enfants MaladesParis, FranceRecruiting
Vian - M. Iashvili Children's Central HospitalTbilisi, GeorgiaCompleted
Tbilisi State Medical University - Givi Zhvania Pediatric Academic ClinicTbilisi, GeorgiaCompleted
Charite Universitaetsmedizin Berlin - Campus Virchow-Klinikum - Sozialpadiatrisches ZentrumBerlin, GermanyCompleted

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04833894