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Study identifier: NCT04824950 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL)

Condition: Primary Mediastinal Large B-cell Lymphoma  ·  Sponsor: Centre Henri Becquerel

PhaseNA
Planned participants87
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare the predictive value in terms of specificity of circulating tumor DNA (ctDNA) and positron emission computed tomography (PET-CT) after 2 cycles of chemotherapy (C2), on the probability of obtaining a metabolic complete response after 4 cycles of induction chemotherapy (C4) in patients with primary mediastinal large B cell lymphoma (PMBL) receiving standard R-CHOP14 or R-ACVBP.

This description comes directly from the study's public registry record.

Talk to the study team

VINCENT CAMUS, MD  ·  +33232082497  ·  vincent.camus@chb.unicancer.fr

RICHARD DORIANE, PhD  ·  +33232082985  ·  doriane.richard@chb.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Centre Hospitalier Lyon SudLyon, FranceNot Yet Recruiting
Centre Henri BecquerelRouen, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04824950