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Study identifier: NCT04822077 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study on Proton Radiotherapy of Thymic Malignancies

Condition: Cardiotoxicity · Pulmonary Toxicity · Thymus Neoplasms  ·  Sponsor: Ass. Prof. Jan Nyman

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicentre non-randomized phase II study of proton beam radiotherapy in patients with thymic epithelial tumours (i.e. thymoma and thymic carcinoma) in the post-operative setting or in inoperable patients with localized disease. Patients not willing or for any reason unsuitable to undergo proton treatment will be asked to participate in a follow-up assessment after the regular photon treatment in the same manner as the included patients. Primary endpoints are:Toxicity (e.g. cardiac and pulmonary toxicity) and Local control at 5 year Secondary endpoints: PFS, Overall survival, Quality of life, measured by EORTC QLQ 30 + LC 13 and relapse pattern

This description comes directly from the study's public registry record.

Talk to the study team

Jan Nyman, Ass.prof.  ·  +46313421000  ·  jan.nyman@oncology.gu.se

Andreas Hallqvist, MD, PhD  ·  +46739845114  ·  andreas.hallqvist@vgregion.se

Always discuss trial participation with your own doctor first.

Locations (3)

Department of Oncology, Norrlands UniversitetssjukhusUmeå, Norrland, SwedenRecruiting
Department of Oncology, Karolinska University HospitalStockholm, Stockholm County, SwedenNot Yet Recruiting
Department of Oncology, Sahlgrenska University HospitalGothenburg, Västra Götaland County, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT04822077