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Study identifier: NCT04817618 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

Condition: C3G  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants98
Who can joinAll sexes, 12 Years to 60 Years
Healthy volunteersNo

About this study

The Primary Completion Date and Study Completion Date have been updated to reflect completion of the adolescent cohort, which has been added to the protocol. The study is designed as a multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the efficacy and safety of iptacopan (LNP023) in complement 3 glomerulopathy.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (87)

Childrens Hospital ColoradoAurora, Colorado, United StatesRecruiting
Nicklaus Childrens HospitalMiami, Florida, United StatesRecruiting
Georgia Nephrology Research InstLawrenceville, Georgia, United StatesCompleted
IN University School of MedIndianapolis, Indiana, United StatesWithdrawn
University of Iowa Health CareIowa City, Iowa, United StatesRecruiting
University of Iowa Health CareIowa City, Iowa, United StatesRecruiting
Johns Hopkins HospitalBaltimore, Maryland, United StatesWithdrawn
Brigham and Womens Hosp Harvard Med SchoolBoston, Massachusetts, United StatesWithdrawn
Hackensack Uni Medical CenterHackensack, New Jersey, United StatesWithdrawn
Albany Medical CenterAlbany, New York, United StatesWithdrawn
Col Uni Med Center New York PresbyNew York, New York, United StatesCompleted
Baylor Scott and White ResearchTemple, Texas, United StatesWithdrawn

+ 75 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04817618