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Study identifier: NCT04812730 Synced from ClinicalTrials.gov · July 29, 2026
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Multimodal Bio-mechanical Analysis of Adult Spinal Deformity With Sagittal Plane Misalignment

Condition: Spinal Deformity  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhaseNA
Planned participants265
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersYes

About this study

A good understanding of the principles of balance is vital to achieve optimal outcomes when treating spinal disorders. A complex interaction of the neuromotor system and muscular recruitment is necessary for ergonomic balance and deliberate displacement of the human body. Sagittal plane misalignment in spinal deformities challenges balance mechanisms used for maintenance of an upright posture. The occurrence of postoperative complications after spinal deformity correction like under-correction of sagittal misalignment, postoperative reciprocal changes in thoracic kyphosis, proximal junctional kyphosis and failure of instrumentation are possibly due to the current state-of-the art inadequate diagnostic work-up. Investigators do not fully understand the roll of vision and exact strategy of recruitment of neuromuscular units (trunk, pelvis, lower limbs) in patients with sagittal plane misalignment during standing and walking. To understand this, a dynamic evaluation of individuals with spinal deformities is needed. Currently there is only very little research performed in the field of clinical balance tests and instrumented movement analysis in patients with spinal deformity. The challenge for future studies is to further unravel the relation between trunk and lower limb movements, grouped into functional movement patterns. Moreover, additional information on trunk and lower limb kinetics and muscle activity (using dynamic electromyography (EMG)) will highly contribute to the …

This description comes directly from the study's public registry record.

Talk to the study team

Lieven Moke  ·  +32 16 34 08 84  ·  lieven.moke@uzleuven.be

Lennart Scheys  ·  +32 16 34 08 85  ·  lennart.scheys@uzleuven.be

Always discuss trial participation with your own doctor first.

Locations (1)

UZ LeuvenLeuven, Vlaams-Brabant, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT04812730