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Study identifier: NCT04807257 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Auger Molecular Therapy (AMT) for Malignant Cutaneous Lesions Treatment

Condition: Malignant Fungating Wound  ·  Sponsor: NanoRay Biotech Co., Ltd.

PhasePhase 1/Phase 2
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human, single-arm, open-label, dose escalating study to determine the safety and the recommended maximum tolerated dose of the AMT in subjects with malignant cutaneous lesions. AMT is a combination therapy of a drug (IUdR) and a device (AUTRON Therapy System). IUdR is an iodinated thymidine analogue that is preferentially incorporated into DNA in rapid growing cells. The AUTRON Therapy System generates characteristic X-Ray photons around 33.4 keV, matching the K-edge energy of Iodine (33.17 keV), which can efficiently induce Auger electron emissions from IUdR in cancer DNA, resulting in extensive DNA damage and cancer cell death.

This description comes directly from the study's public registry record.

Talk to the study team

Irene Lee, MS  ·  + 886 2 3393 1388  ·  irene.lee@qps-taiwan.com

Always discuss trial participation with your own doctor first.

Locations (1)

Taipei Medical University HospitalTaipei, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT04807257