Condition: Malignant Pleural Effusion · Non-small Cell Lung Cancer · Sponsor: Naestved Hospital
Oncological treatment of patients with disseminated non-small cell lung cancer (NSCLC) is depending on the status of programmed death-ligand 1 (PD-L1), anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR), so called oncodrivers. These can be measured in pleural fluid, but the prevalence is uncertain. In a prospective study, the research team aim to measure PD-L1, ALK and EGFR in patients with pleural fluid cytology positive for NSCLC to report the prevalence. Also, the study will investigate if the chance of obtaining oncodriver status is depending on the volume analysed and how the lack of oncodrivers influence the following work-up.
This description comes directly from the study's public registry record.
Katrine Fjaellegaard, MD · 31924375 · kafj@regionsjaelland.dk
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| Næstved Sygehus, department of pulmonary medicine | Næstved, Region Sjælland, Denmark | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04806412