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Study identifier: NCT04796714 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE

Condition: Atrial Fibrillation · Atrial Appendage · Anticoagulants  ·  Sponsor: University Hospital, Bordeaux

PhasePhase 4
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The APPENDAGE study is a phase 4 multicentre randomized opened clinical trial comparing 2 different antithrombotic strategies following left atrial appendage closure (LAAC) in patients with non valvular atrial fibrillation (AF). The primary objective of the study is to evaluate the efficacy of Aspirin versus Aspirin + Clopidogrel after LAAC by comparing the occurrence of ischemic lesions on cerebrovascular magnetic resonance imaging (MRI) studies.

This description comes directly from the study's public registry record.

Talk to the study team

Zakaria JALAL, MD  ·  (0)5 57 65 64 65  ·  zakaria.jalal@chu-bordeaux.fr

Amandine RUISSEL  ·  (0)5 57 62 32 29  ·  amandine.ruissel@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Bordeaux University HospitalPessac, FranceRecruiting
Toulouse University HospitalToulouse, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04796714