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Study identifier: NCT04791579 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Antibiotic Prophylaxis for Neurogenic Bladder Botox

Condition: Neurogenic Bladder · Post-operative Urinary Tract Infections  ·  Sponsor: University of Alberta

PhasePhase 2
Planned participants160
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Injection of Botox into the bladder is a procedure used to treat neurogenic overactive bladder at the Dianne and Irving Kipnes Urology Centre in the Kaye Edmonton Clinic. A common complication following bladder Botox is bladder infection. There are no well-studied preventative antibiotics given at the time of bladder Botox for the reduction of post-operative bladder infection. We are proposing a research study that will randomize participants into two groups - one receiving antibiotics and the other receiving placebo pills following bladder Botox. The main goal of our study is to determine if preventative antibiotics at the time of bladder Botox injection reduces post-operative bladder infection. It will provide a valuable learning opportunity for a trainee starting their academic career through working closely with established researchers across two disciplines. We hope the results of our study can ultimately be used to improve outcomes and safety for a common Urologic procedure. In addition, findings from our study could help reduce unnecessary use of antibiotics resulting in cost savings in the health care system and reduction in the risk of antibiotic resistance.

This description comes directly from the study's public registry record.

Talk to the study team

Joseph LaBossiere, MD FRCSC  ·  780-407-5958  ·  josephlpmd@gmail.com

Paul Groves, MR FRCSC  ·  709-763-0456  ·  pgroves@ualberta.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University of AlbertaEdmonton, Alberta, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04791579