Condition: Major Depressive Disorder · Sponsor: Mclean Hospital
Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived control disruptions in MDD remain poorly understood. Using functional magnetic resonance imaging with a novel "value of control task" in conjunction with a prospective design, this study will provide a comprehensive understanding of stress and perceived control related mechanisms in female adolescents with MDD and will examine stress-induced disruptions in perceived control as a predictor of "real world" expressions of maladaptive coping and anhedonia.
This description comes directly from the study's public registry record.
Emily L Belleau, PhD · 6178554245 · ebelleau@mclean.harvard.edu
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| McLean Hospital | Belmont, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04788524