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Study identifier: NCT04786873 Synced from ClinicalTrials.gov · July 27, 2026
● Completed

A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is

Condition: Growth Hormone Deficiency  ·  Sponsor: AEterna Zentaris

PhasePhase 3
Planned participants101
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

This research study will find out if a new growth hormone stimulation test is safe and works as well as other tests to diagnose growth hormone deficiency (GHD) in children. The stimulation test will use a new growth hormone stimulating substance called macimorelin. By now, only adults in the USA can get this new stimulation test. The results of this study are expected to help children and teenagers with suspected GHD to get the macimorelin stimulation test. The macimorelin test will be compared to a clonidine and an arginine test. Both are known standard stimulation tests. Altogether two macimorelin tests are planned to be performed in the study, to show how repeatable macimorelin tests results are (under a set of similar conditions).

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (45)

Angel Wing Clinic For Children With DiabetesTucson, Arizona, United States
Pediatric Endocrine Associates, p.c.Greenwood Village, Colorado, United States
John Hopkins All Children's HospitalSt. Petersburg, Florida, United States
Emory Healthcare-Children's CenterAtlanta, Georgia, United States
St. Luke's Children's EndocrinologyBoise, Idaho, United States
University of Minnesota, Masonic Children's HospitalMinneapolis, Minnesota, United States
The Children's Mercy Hospital - BroadwayKansas City, Missouri, United States
Icahn School of Medicine at Mount SinaiNew York, New York, United States
Children's Hospital at MontefioreThe Bronx, New York, United States
UNC HospitalsChapel Hill, North Carolina, United States
Alchemi Research CenterRosharon, Texas, United States
Multicare Health SystemTacoma, Washington, United States

+ 33 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04786873