← Eichor
Study identifier: NCT04786262 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Condition: Diabetes Mellitus, Type 1 · Impaired Hypoglycemic Awareness · Severe Hypoglycemia  ·  Sponsor: Vertex Pharmaceuticals Incorporated

PhasePhase 3
Planned participants52
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study will evaluate the safety, tolerability and efficacy of VX-880 infusion in participants with Type 1 diabetes (T1D) and impaired awareness of hypoglycemia (IAH) and severe hypoglycemia.

This description comes directly from the study's public registry record.

Talk to the study team

Medical Information  ·  617-341-6777  ·  medicalinfo@vrtx.com

Always discuss trial participation with your own doctor first.

Locations (29)

City of HopeDuarte, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
UHealth Diabetes Research InstituteMiami, Florida, United StatesRecruiting
Northwestern Organ Transplant CenterChicago, Illinois, United StatesCompleted
University of ChicagoChicago, Illinois, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
University of Pittsburgh Medical Center MontefiorePittsburgh, Pennsylvania, United StatesRecruiting
Baylor Scott and White Research InstituteDallas, Texas, United StatesRecruiting
VCU Medical Center, RichmondRichmond, Virginia, United StatesRecruiting
University of WisconsinMadison, Wisconsin, United StatesRecruiting

+ 17 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT04786262