Condition: Coronary Disease · Sponsor: Henan Institute of Cardiovascular Epidemiology
Remote Ischemic preconditioning (RIPC) has been reported to improve myocardial microcirculation, promote collateral circulation recruitment, and improve myocardial perfusion in patients.Two large randomized controlled trials demonstrated a perioperative cardioprotective effect of RIPC (reduced troponin levels), but did not find that a single preoperative RIPC improved long-term outcomes of coronary artery bypass grafting(CABG).The effect of a single RIPC before CABG may be too short. This study aims to investigate whether long-term RIPC improved myocardial perfusion in patients 3 months and 6 months after CABG surgery , and to detect changes in blood vascular endothelial growth factor, Nitrc Oxide, adenosine，and Endothelin-1, and to observe MACCE event rates at 12 months.
This description comes directly from the study's public registry record.
Quan Guo, MD · +8615670510031 · xinyiguoquan@163.com
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| Fuwai central China cardiovascular Hospital | Zhengzhou, Henan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04779008