Condition: Non-Small Cell Lung Cancer · Sponsor: Hunan Province Tumor Hospital
The study is a prospective multi-cohort clinical study. Cohort A is evaluating the efficacy and safety of IBI318 in combined with lenvatinib in advanced NSCLC patients who had failed first-line PD-1/PD-L1 inhibitor therapy. Cohort B is the efficacy and safety of advanced NSCLC with EGFR-sensitive mutation /ALK fusion after EGFR-TKI /ALK-TKI treatment resistance. Cohort C is the efficacy and safety of first-line treatment of advanced NSCLC with negative PD-L1 expression and EGFR, ALK, and ROS1 wild-type. After being screened to meet the inclusion criteria, they will receive IBI318 combined with lenvatinib until the disease progresses, death, toxicity is intolerable, informed consent is withdrawn, new anti-tumor therapy is started, or the treatment is terminated for other reasons specified in the plan.
This description comes directly from the study's public registry record.
Yongchang Yongchang, MD · +8613873123436 · zhangyongchang@csu.edu.cn
Nong Yang, MD · +8613055193557 · yangnong0217@163.com
Always discuss trial participation with your own doctor first.
| Hunan Cancer hospital | Changsha, Hunan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04777084