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Study identifier: NCT04774718 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Condition: ALK Fusion-positive Solid or CNS Tumors  ·  Sponsor: Hoffmann-La Roche

PhasePhase 1/Phase 2
Planned participants42
Who can joinAll sexes, N/A to 17 Years
Healthy volunteersNo

About this study

This study will evaluate the safety, pharmacokinetics, and efficacy of alectinib in children and adolescents with ALK fusion-positive solid or CNS tumors for whom prior treatment has proven to be ineffective or for whom there is no satisfactory standard treatment available.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GO42286 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (33)

Lucile Packard Children's HospitalPalo Alto, California, United StatesRecruiting
Johns Hopkins All Children's HospitalSt. Petersburg, Florida, United StatesRecruiting
University of Michigan, C.S. Mott Children's HospitalAnn Arbor, Michigan, United StatesRecruiting
Children's MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesActive Not Recruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting
St. Jude Children'S Research HospitalMemphis, Tennessee, United StatesRecruiting
Sydney Children's HospitalRandwick, New South Wales, AustraliaRecruiting
Royal Children's HospitalParkville, Victoria, AustraliaRecruiting
Hospital de Cancer de BarretosBarretos, São Paulo, BrazilRecruiting
Graacc-Grupo de Apoio ao adolescente e a crianca com cancerSão Paulo, São Paulo, BrazilRecruiting
The Hospital for Sick ChildrenToronto, Ontario, CanadaRecruiting

+ 21 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04774718