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Study identifier: NCT04772963 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)

Condition: Arteriovenous Malformations  ·  Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

PhaseN/A
Planned participants300
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Cerebral and medullary arteriovenous malformations (AVMs) lead to arterial and venous networks to communicate pathologically, creating an arteriovenous shunt. The occurrence of intracranial haemorrhage is the most important prognostic factor of AVMs because it is associated with a significant morbidity and mortality. The genetic, molecular and cellular mechanisms that cause vascular malformations of the central nervous system are partially known and the influence of genetic damage on the prognosis of AVMs is poorly known.

This description comes directly from the study's public registry record.

Talk to the study team

Stanislas Smajda, MD  ·  0148036454  ·  ssmajda@for.paris

Amélie Yavchitz, MD  ·  0148036454  ·  ayavchitz@for.paris

Always discuss trial participation with your own doctor first.

Locations (1)

HOPITAL FONDATION Adolphe de ROTHSCHILDParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04772963