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Study identifier: NCT04770012 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Condition: Cardiac Allograft Vasculopathy · Heart Transplant  ·  Sponsor: Ottawa Heart Institute Research Corporation

PhasePhase 3
Planned participants135
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cardiac allograft vasculopathy is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. The research team is investigating whether early antiplatelet therapy post heart transplant can prevent the development of CAV. This study will determine the feasibility of a large multicenter randomized placebo-controlled trial to answer this question.

This description comes directly from the study's public registry record.

Talk to the study team

Sharon Chih  ·  613-696-7000  ·  schih@ottawaheart.ca

Heather Ross  ·  heather.ross@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (3)

St.Pauls HospitalVancouver, British Columbia, CanadaRecruiting
University of Ottawa Heart InstituteOttawa, Ontario, CanadaRecruiting
Toronto General Hospital UHNToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04770012