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Study identifier: NCT04764331 Synced from ClinicalTrials.gov · July 28, 2026
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A Pilot Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia

Condition: Central Centrifugal Cicatricial Alopecia  ·  Sponsor: Wake Forest University Health Sciences

PhaseNA
Planned participants5
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

Central centrifugal cicatricial alopecia (CCCA) is form of scarring hair loss that predominately affects middle-aged women of African descent.1 . Clinically, the natural progression of CCCA starts at the crown as roughly circular scarred patches, which evolve into scarred areas increasing in size circumferentially. Characteristically, the scar is often smooth and shiny, and the hair density in the affected area is frequently decreased. The hair remaining in the scarred areas is more brittle and shorter than the hair in unaffected areas. Since CCCA is a scarring disorder, it can cause permanent hair loss, dyesthesias, and psychological distress which can affect overall quality of life. Affected individuals may complain of pruritus, pain, or tenderness.2 The management of CCCA is challenging due to limited current treatments and a lack of randomized controlled trails. Management focuses on behavioral and styling modifications, in addition to symptomatic relief. Any potentially damaging hair care practices such as chemical relaxers, heat application to the scalp, and the use of hardening gels and sprays are discouraged.3 Many commonly used therapies are anti-inflammatory in nature, including intralesional steroids, topical steroids, oral antibiotics and increased frequency of hair washing with antidandruff shampoos.4 These treatments not only lead to improvement in pruritus and tenderness, but in some cases result in increased hair density.5 Since there is limited investigation…

This description comes directly from the study's public registry record.

Talk to the study team

Irma M Richardson, MHA  ·  336-716-2903  ·  irichard@wakehealth.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Wake Forest School of Medicine - Dermatology ClinicWinston-Salem, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04764331