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Study identifier: NCT04763655 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neural Biomarkers of Electroconvulsive Therapy Response

Condition: Electroconvulsive Therapy Treated Patients  ·  Sponsor: Northwell Health

PhaseNA
Planned participants75
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

In the proposed study, the investigators will utilize resting-state functional MRI (fMRI) and structural MRI-based electrical field modeling to study the effect of electroconvulsive therapy on human neural circuitry. Our study will recruit patients who are beginning treatment with bilateral electroconvulsive therapy (N=75). Our design will be longitudinal where patients will be followed up until their 8th week electroconvulsive therapy clinically. The primary measure of interest will be the slope of clinical change estimated with mixed effect modeling (see Approach). Secondary measures will be the cognitive performance change between baseline and the 8th week electroconvulsive therapy time point.

This description comes directly from the study's public registry record.

Talk to the study team

Heela Azizi  ·  718-470-8165  ·  hazizi1@northwell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Zucker Hillside HospitalGlen Oaks, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04763655