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Study identifier: NCT04762199 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

Condition: Advanced Lung Non-Small Cell Carcinoma · Metastatic Lung Non-Small Cell Carcinoma · Stage IV Lung Cancer AJCC v8  ·  Sponsor: Emory University

PhasePhase 1
Planned participants69
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase Ib trial evaluates the best dose and side effects of MRX-2843 when given in combination with osimertinib in treating patients with EGFR gene mutant non-small cell lung cancer that has spread to other places in the body (advanced). MRX-2843 and osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Conor Steuer, MD  ·  404-727-5658  ·  csteuer@emory.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Emory University Hospital/Winship Cancer InstituteAtlanta, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04762199