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Study identifier: NCT04753970 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Retina is a Marker for Cerebrovascular Heath

Condition: Cerebral Small Vessel Diseases · Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy · Cerebral Microbleeding  ·  Sponsor: Mayo Clinic

PhasePhase 1/Phase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Cerebral small vessel disease (SVD), present in 80-94% of adults over age 65 years, increases the risk of stroke by 2-fold, and dementia by 2.3-fold. There is currently no treatment to slow SVD progression. This study aims to test whether impaired cerebral and retinal vasoreactivity may serve as biomarker for SVD progression, and to evaluate the safety and efficacy of cilostazol (antiplatelet agent with vasodilatory and anti-inflammatory properties) for the treatment of SVD.

This description comes directly from the study's public registry record.

Talk to the study team

Meredith McDonald  ·  904-953-4200  ·  mcdonald.meredith@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Mayo Clinic FloridaJacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04753970