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Study identifier: NCT04747912 Synced from ClinicalTrials.gov · July 28, 2026
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Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

Condition: Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia · ph+ Acute Lymphoblastic Leukemia  ·  Sponsor: University of Chicago

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study will add an anti-cancer drug (called inotuzumab ozogamicin also known as "InO") to treatment for participants with newly diagnosed Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). Doctors leading this study hope to learn if adding InO to standard induction treatment for Ph+ ALL will lead to quicker, complete molecular remission (where the disease is not detectable even with very sensitive testing techniques). The purpose of this research is to gather information regarding the effectiveness of InO in newly-diagnosed Ph+ ALL patients that have not yet received treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Cancer Clinical Trials Office  ·  1-855-702-8222  ·  cancerclinicaltrials@bsd.uchicago.edu

Wendy Stock, MD  ·  773-834-8982  ·  PhaseIICRA@medicine.bsd.uchicago

Always discuss trial participation with your own doctor first.

Locations (1)

University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04747912