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Study identifier: NCT04745390 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer

Condition: Hepatocellular Carcinoma · Liver Metastases  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Radiation is a standard treatment option for patients with liver cancer. Unfortunately, the tumour grows after radiation in many patients and radiation can harm normal tissues. A new treatment using a specialized radiation procedure called Stereotactic body radiotherapy (SBRT) may increase the chance to control liver cancer and reduce the chance of harm to normal tissues. SBRT allows radiation treatments to be focused more precisely, and be delivered more accurately than with older treatments. SBRT has become a routine treatment. Further research has found that specialized computer programs can possibly guide the selection of an appropriate SBRT dose. This is called radiobiological guidance. However, this has not yet been proven to improve outcomes and/or reduce toxicity. Therefore, the purpose of this study is to find out if SBRT at standard dose versus SBRT guided by radiobiological techniques is better for you and your liver cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Morgan Black  ·  519-685-8500  ·  morgan.black@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (1)

London Regional Cancer ProgramLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04745390