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Study identifier: NCT04742959 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Condition: Advanced Solid Tumor · Cholangiocarcinoma · HER2-negative Breast Cancer  ·  Sponsor: TransThera Sciences (Nanjing), Inc.

PhasePhase 1/Phase 2
Planned participants203
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase Ib/II, multicenter, open-label study to evaluate the safety and preliminary efficacy of TT-00420 tablet, as monotherapy or in combination regimens, in patients with advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (6)

City of HopeDuarte, California, United States
The University of ChicagoChicago, Illinois, United States
Rutgers Cancer InstituteNew Brunswick, New Jersey, United States
Gabrail Cancer Center ResearchCanton, Ohio, United States
UT Southwestern Medical CenterDallas, Texas, United States
MD Anderson Cancer CenterHouston, Texas, United States

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Source record: clinicaltrials.gov/study/NCT04742959