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Study identifier: NCT04732910 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators

Condition: Cystic Fibrosis  ·  Sponsor: Charite University, Berlin, Germany

PhaseN/A
Planned participants500
Who can joinAll sexes, 6 Months to no upper limit
Healthy volunteersNo

About this study

This observational study evaluates the effect of therapy with cystic fibrosis transmembrane regulator (CFTR) modulators on CFTR function measured by the CFTR biomarker intestinal current measurement (ICM), nasal potential difference (NPD) and sweat chloride in a post-approval setting in patients with cystic fibrosis (CF).

This description comes directly from the study's public registry record.

Talk to the study team

Simon Y Graeber, MD  ·  +4930 450 566 587  ·  simon.graeber@charite.de

Always discuss trial participation with your own doctor first.

Locations (4)

Charité - Universitätsmedizin BerlinBerlin, State of Berlin, GermanyRecruiting
Justus-Liebig-University GiessenGiessen, GermanyRecruiting
Hannover Medical SchoolHanover, GermanyRecruiting
University of HeidelbergHeidelberg, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT04732910